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Hawaii Center for Neuromodulation

Neuromodulation is technology that acts directly upon nerves. It is altering or modulating nerve activity by delivering electrical impulses directly to a target area.   Neuromodulation can be life changing and enhance the quality of life in individuals who suffer severe chronic neurological conditions such as persistent pain; spinal injury; spasticity; movement disorders; epilepsy; Parkinson’s disease, tremors and stroke.

Neuromodulations Therapies offered in Hawaii:

Vagal Nerve Stimulation (VNS) – Epilepsy, Str oke Recovery

Deep Brain Stimulation (DBS) – Parkinson’s disease & Epilepsy

Spinal Cord Stimulation (SCS) – Failed Back Surgery, MS, Complex Regional Pain Syndrome, Chronic Painful Neuropathy or Plexopathy 

Neuromodulation Research Modalities in Hawaii

Brain Computer Interface (BCI) & Neural Network Research Lab.
Neurotechnology & AI (Artificial Intelligence) Research Lab.

 Hawaii Center for Neuromodulation at Hawaii Pacific Neuroscience in collaboration other neuromodulations centers in US as well as experts in neurology, neurosurgery, biomedical engineering, neuroradiology, international partners work together to provide cutting edge neuromodulation therapies to patients in Hawaii who could benefit from them and also conduct active research to advance understanding of how neuromodulation can drive “bench to bedside” translational science to benefit patients in Hawaii and worldwide suffering from chronic refractory neurological conditions.

Center for Neuromodulation is directed by Kore Kai Liow, MD, Neurologist and Clinical Professor of Medicine (Neurology), University of Hawaii John Burns School of Medicine who has successfully implanted over 300 patients with neuromodulation devices over the last 25 years and have seen how they positively changed their lives.  He works and collaborates with a team of neuroscience specialists including neurologists, pain specialists, neurosurgeons, neurorehabilitation specialists to choose the right treatment plan, which may include medications and counselling, based on individual patient’s needs and medical situation.

Center for Neuromodulation is conducting multidisciplinary clinic at either

Hawaii Pacific Neuroscience – HONOLULU (St Francis Liliha) or
Hawaii Pacific Neuroscience – WEST OAHU (Waikele)

Clinic Call/text (808) 261-4476, Research (808) 564-6141


Meet Our

Multidisciplinary Team

Kore Kai Liow, M.D., F.A.C.P., F.A.A.N.

Neuroscience Chair

Director, Memory Disorders Center, Comprehensive Epilepsy Center, Neuro COVID Clinic, Center for Neuromodulation, Hawaii Pacific Neuroscience
Principal Investigator, Clinical Research Center, BRITL (Brain Research, Innovation & Translation Labs) BCI (Brain Computer Interface) & Brain Mapping Lab
Clinical Professor of Medicine (Neurology), Graduate Faculty, Clinical & Translational Research, University of Hawai`i John A. Burns School of Medicine

Nicholas Anderson, MD

Sleep Medicine

Director, Sleep and Insomnia Center
Clinical Assistant Professor of Family Medicine,
University of Hawai`i John Burns School of Medicine

Darren DuGas, M.D.


Director, Video-EEG Epilepsy Monitoring Unit (EMU)
Co-Director, Comprehensive Epilepsy Center
Sub- Investigator, Epilepsy Research Unit

Natalia Gonzalez Caldito, M.D.


Director, MS & Neuroimmunology Center
Director, ALS & Neuromuscular Center & IV Infusion Center
Sub investigator, MS & Neuroimmunology & Neuromuscular Research Unit

Eonjung Angeline Kim, M.D.


Director, Headache & Facial Pain Center
Sub- Investigator, Headache Research Unit

Janette Abramowitz, M.D.


Research Faculty, Brain Mapping Lab, Brain Research, Innovation & Translation Labs
Residency: Combined Neurology & Psychiatry University of Massachusetts Medical School Medical School: University of Massachusetts Medical School

Alexander Takayesu, M.D., M.P.H.


Périnatal Psychiatry, Post Partum Dépression
Assistant Professor of Psychiatry, University of Hawaii John A Burns School of Medicine
SubInvestigator, Center for Psychiatric Neuroscience

Paul Smith, M.D.

Lifestyle Medicine

Director, Self Care & Wellness Center
Sub-investigator, Clinical Research Center
Clinical Assistant Professor of Medicine (Neurology), University of Hawai`i John A. Burns School of Medicine

Chris Larrinaga, ARPN-BC, MSN, CNRN

Neurology, Neuroscience

Sleep Medicine
Sub-Investigator, Clinical Research Center

Nicole Evans, PA-C

Neurology, Neuroscience

Sub-Investigator, Clinical Research Center


Neurology, Neuroscience

Memory Disorders
Sub-Investigator, Clinical Research Center

Qing X. Li PhD

Basic Science, Neuroscience

Professor, Department of Molecular Biosciences and Bioengineering, College of Tropical Agriculture and Human Resources University of Hawai‘i at Mānoa, Honolulu

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