There is currently no widely available tool to measure someone’s memory or cognitive abilities to look for early signs of Alzheimer’s or monitor the efficacy of treatment or progression. Traditional memory testing are subjective and depends on patients’ performance thus we depend on invasive test like spinal tap and use of radioactive substance injected into body to look for Alzheimer’s biomarker in the brain which are not readily accessible in island communities such as
Hawaii state and many rural communities in US. Lack of readily available testing often lead to delayed diagnosis & intervention and eventually poor long term outcome.
The Hawaii Memory Disorders Center & Alzheimer’s Research Unit collaborates with the EEG Lab & Brain Research Innovation & Translation Labs to launch the Hawaii ANNE (Alzheimer’s Neural Network EEG) research project to investigate whether noninvasive EEG brain signals which measures synaptic neuronal network brain electrical activities can serve as a readily available and cost-effective tool to access the health of the brain and its function like memory and cognitive abilities?
Abnormal Temporal Slowing on EEG Findings in Preclinical Alzheimer’s Disease Patients with the ApoE4 Allele: A Pilot Study Kim N, Tan C, Ma E, Kutlu S, Carrazana E, Vimala V, Viereck J, Liow K. (October 28, 2023) Cureus 15(10): e47852. DOI 10.7759/Cureus.47852.
Evaluating Whether EEG Could Predict Alzheimer’s Disease Onset in Preclinical Patients with the ApoE4 Allele: An Update. Kim N, Tan C, Ma E,
Kutlu S, Mitchell C, Carrazana E, Viereck J, Vajjala V, Liow K. 2022 2022 American Epilepsy Society Meeting, Nashville, TN
“Our Hawaii patients, caregivers, families, neurologists & researchers are honored to be able to play a role to contribute to this important ground breaking research to develop a noninvasive, widely available and cost effective tool for Alzheimer’s Disease to serve our island and rural populations, ” Kore Kai Liow, MD, Director, Hawaii Memory Disorders Center Principal Investigator, Alzheimer’s Research Unit, Clinical
Professor of Medicine (Neurology), Graduate Faculty, Clinical & Translational Research, University of Hawai`i John Burns School of Medicine. Dr. Liow is a research neurologist trained in clinical neurophysiology & EEG at National Institutes of Health (NIH), Bethesda, Maryland. Info: ANNE Research Lab PI email@example.com