(front) medical students Michael Read, janette Keola, Kirra Borrelo, Nathan Kim Neurologist Kore Kai Liow, MD, Shay Nakahira, Kaylie Yamauchi, Sarah Hogue, Research staffs (back row) Kelly Asahi, Jason Edwards, Sam Kim, John Seib, Qi Zhi, DNP, MPH, Ena Zhu
There is currently no widely available tool to measure someone’s memory or cognitive abilities to look for early signs of Alzheimer’s or monitor the efficacy of treatment or progression. Traditional memory testing are subjective and depends on patients’ performance thus we rely on invasive test like spinal tap and use of radioactive substance injected into body to look for Alzheimer’s biomarker in the brain which are not readily accessible in island communities such as Hawaii state and many rural communities in US. Lack of readily available testing often leads to delayed diagnosis & intervention and eventually poor long-term outcome.
The Hawaii Memory Disorders Center & Alzheimer’s Research Unit collaborates with the Advance Brain Monitoring to launch the Hawaii ANNE (Alzheimer’s Neural Network EEG) Lab dedicated to develop an easily accessible, noninvasive, nontoxic and cost effective tool to measures synaptic neuronal network brain electrical activities using BEAM™ (Biomarker based Electrophysiology Advanced Brain Monitoring). BEAM is a proven EEG platform developed using machine learning AI algorithms to map the progression of cognitive decline across the dementias.
“Our Hawaii patients, caregivers, families, neurologists & researchers are honored to be able to play a role to contribute to this important ground breaking research to develop a noninvasive, widely available and cost effective tool for Alzheimer’s Disease to serve our island and rural populations, ” Kore Kai Liow, MD, Director, Hawaii Memory Disorders Center Principal Investigator, Alzheimer’s Neural Network EEG (ANNE) Research Lab, Clinical Professor of Medicine (Neurology), Graduate Faculty, Clinical & Translational Research, University of Hawai`i John Burns School of Medicine. Dr. Liow is a research neurologist trained in clinical neurophysiology & EEG at National Institutes of Health (NIH), Bethesda, Maryland. Info: kliow@hawaii.edu
Nashville, TN, Dec 2022
EEG Predicting Alzheimer’s Disease Onset in Preclinical Patients with the ApoE4 Allele: An Update on EEG Findings
BEAM™ is a new test used by neurologist combining EEG with neurocognitive testing.
In addition to routine EEG, you will be asked to perform a series of active and passive visual, auditory tasks to assess attention, memory and emotion.
Using the latest AI- Machine Learning technology, a set of unique brain “fingerprints” or cognitive biomarkers unique to the patient will be generated in comparison with thousands of normal data to help your doctor to:
-making accurate diagnosis of your condition
-quantify the severity of the condition
-tracking disease progression
-assessing whether a treatment or intervention has been effective
For more information: https://hawaiineuroscience.com/alzheimer-eeg-project/
https://www.advancedbrainmonitoring.com/applications/biomarkers
“Our Hawaii patients, caregivers, families, neurologists & researchers are honored to be able to play a role to contribute to this important ground breaking research to develop a noninvasive, widely available and cost effective tool for Alzheimer’s Disease to serve our island and rural populations, ” Kore Kai Liow, MD, Director, Hawaii Memory Disorders Center Principal Investigator, Alzheimer’s Research Unit, Clinical
Professor of Medicine (Neurology), Graduate Faculty, Clinical & Translational Research, University of Hawai`i John Burns School of Medicine. Dr. Liow is a research neurologist trained in clinical neurophysiology & EEG at National Institutes of Health (NIH), Bethesda, Maryland. Info: ANNE Research Lab PI kliow@hawaii.edu
