Questions, contact BRAIN Program Director Kore Kai Liow, MD, [email protected]

Info:   BRAIN (Brain Research And Neuroscience)    BRAIN Summer Internship Program

Mettias A, Iwai K, Edwards-Calma K, Miura H, Wright DD, Nakamura R, Cheung AJ, Anderson N, Liow KK, Carrazana E. Insights into obstructive sleep apnea severity and treatment adherence in Native Hawaiian and Pacific Islanders. Sleep Med. 2025 Apr 11;131:106504. doi: 10.1016/j.sleep.2025.106504. Epub ahead of print. PMID: 40239596.

 

Lyons P, Wheless J, Verner R, Ferreira J, Liow K, Valeriano J, Motamedi G, Giannicola G, Nichol K. Vagus nerve stimulation in Lennox-Gastaut syndrome: Twenty-four-month data and experience from the CORE-VNS study. Epilepsia. 2025 Feb 8;. doi: 10.1111/epi.18289. [Epub ahead of print] PubMed PMID: 39921595.

 

Siriwardhana C, Carrazana E, Liow K. Survival disparities among Alzheimer’s disease patients in Hawaii. J Alzheimers Dis. 2025 Mar;104(1):116-128. doi: 10.1177/13872877251314144. Epub 2025 Jan 26. PubMed PMID: 39865689.

French JA, Porter RJ, Perucca E, Brodie MJ, Rogawski MA, Harden C, Qian J, Rosenblut CL, Kenney C, Beatch GN. Interim analysis of the long-term efficacy and safety of azetukalner in an ongoing open-label extension study following a phase 2b clinical trial (X-TOLE) in adults with focal epilepsy. Epilepsia Open. 2025 Mar 7;. doi: 10.1002/epi4.70015. [Epub ahead of print] PubMed PID: M40053315.

 

Wong JH, Gan A, Nguyen L, El-Hage LZ, Kawaakoa K, Roman M, Siriwardhana C, Carrazana E, Liow KK. Racial Disparities in Cardiometabolic Disorders Among Alzheimer’s Disease Patients: A Study on Native Hawaiians and Pacific Islanders. Cureus. 2024 Dec;16(12):e76197. doi: 10.7759/cureus.76197. eCollection 2024 Dec. PubMed PMID: 39840157; PubMed Central PMCID: PMC11750210.

 

Kim KM, Lew RJ, Higashihara TJ, Yamashita S, Pang M, Stafford M, Goo C, Teehera KB, Luu K, Ho R, Carrazana E, Viereck J, Liow KK, Ghaffari-Rafi A. Differences in tumor size, clinical, demographic, and socioeconomic profiles of central nervous system tumors among a racially diverse cohort: A retrospective case-control study. Surg Neurol Int. 2024;15:459. doi: 10.25259/SNI_190_2024. eCollection 2024. PubMed PMID: 39777174; PubMed Central PMCID: PMC11704430

 

Borrello K, Nakahira S, Fontana P, Guittu D, Hunter C, Lee A, Jahansooz J, Weldon E 4th, Roman M, Ahn HJ, Carrazana E, Liow K. Progression of Dopaminergic Therapy Changes in Parkinson’s Disease in Asian and Native Hawaiian and Pacific Islander Populations. Mov Disord Clin Pract. 2024 Nov 18;. doi: 10.1002/mdc3.14280. [Epub ahead of print] PubMed PMID: 39555887.

 

Meropol SB, Norris CJ, Frontera JA, Adeagbo A, Troxel AB. The National Institutes of Health COVID-19 Neuro Databank/Biobank: Creation and Evolution. Neuroepidemiology. 2024 Jun 26;:1-13. doi: 10.1159/000539830. [Epub ahead of print] PubMed PMID: 38934169.

 

Tiffany Cava Morden F, Xin Liang B, Nguyen L, Carrazana E, Ghaffari-Rafi A, Kai Liow K. Partial Rhombencephalosynapsis Presenting in an Adult with Cerebello-Trigeminal-Dermal Dysplasia. Epilepsy Behav Rep. 2024;27:100688. doi: 10.1016/j.ebr.2024.100688. eCollection 2024. PubMed PMID: 39050404; PubMed Central PMCID: PMC11268192.

 

Liow K, Wheless JW, Cook DF, Rabinowicz AL, Carrazana E. Diazepam nasal spray administration is effective to control seizure clusters irrespective of time of day. Front Neurol. 2024;15:1335421. doi: 10.3389/fneur.2024.1335421. eCollection 2024. PubMed PMID: 38854958; PubMed Central PMCID: PMC11157958.

 

Lee AY, Jahansooz JR, Guittu D, Suzuki R, Pak L, Ishikawa KM, Goo C, Chen JJ, Carrazana E, Viereck J, Liow KK. Barriers to Alzheimer Disease Clinical Trial Participation in a Minority Population. Cogn Behav Neurol. 2024 Mar 1;37(1):40-47. doi: 10.1097/WNN.0000000000000359. PubMed PMID: 37878413; PubMed Central PMCID: PMC10948321.

 

Weldon EJ, Nakamura RW, Van T, Goo C, Lee AY, Jahansooz JR, Carrazana E, Liow KK. Exercise and Recovery Following Mild-to-Moderate Traumatic Brain Injury in the Community Setting. Cureus. 2024 Feb;16(2):e53459. doi: 10.7759/cureus.53459. eCollection 2024 Feb. PubMed PMID: 38435185; PubMed Central PMCID: PMC10909398.

The Safety and Effectiveness of Dual Calcitonin Gene-Related Peptide (CGRP) Therapies for Migraine Treatment: A Focus on Small Molecule Antagonist and Ligand Monoclonal Combinations (P9-12.010).  ALee, HH, Cheung AJ, Lee AY, Jahansooz JR, Weldon EJ, Ishikawa KM, Yoshioka R, Woo MI, Liquard L,  Carrazana E, Liow, KK. American Academy of Neurology 2025 Annual Meeting, April 7, 2025, San Diego, California. https://doi.org/10.1212/WNL.0000000000208371

 

Unveiling Disparities in AANHPI: A Comprehensive Analysis of Etiology, Presentation, and Treatment in Peripheral Neuropathy (P9-11.031). Cheung AJ, Kim L, Woo J, Wright DD, Nakamura R, Matsunaga M, Carrazana E, Liow,KK. American Academy of Neurology 2025 Annual Meeting,  Unveiling Disparities in AANHPI: A Comprehensive Analysis of Etiology, Presentation and Treatment in Peripheral Neuropathy, April 8, 2025, San Diego, California. https://doi.org/10.1212/WNL.0000000000208909

 

Are There Differences in Spinal Cord Involvement Among the Ethnocultural Groups of Hawaii? Bellatti S, Romero J, Muniz S, Chang E, Hong B, Nakamura R, Cheung AJ, Wright DD, Ishikawa K, Carrazana E, Liow K. A Multiple Sclerosis Pilot Study: American Academy of Neurology’s Annual Meeting, 2025. P9-1.005. San Diego, CA. April 2025 https://doi.org/10.1212/WNL.000000000020841.

 

Exploring Bilateral Carpal Tunnel Syndrome in Underserved Communities: A Focus on AANHPI Populations and Risk Factors (P4-11.030).  Ryan Nishi, Cadie Young, Ysabella Perez, Anita Cheung, Ddre wright, Ryan Nakamura, Kyle Ishikawa, Natalia Gonzalez Caldito, Enrique Carrazana, and Kore Liow..  American Academy of Neurology’s Annual Meeting, 2025. P9-1.005. San Diego, CA. April 2025.https://doi.org/10.1212/WNL.00000000002127

 

Mettias A, Iwai K, Edwards-Calma K, Miura H, Wright DD, Nakamura R, Cheung AJ, Liow KK, Carrazana E, Anderson N. Exploring Drivers of PAP Therapy Adherence and OSA Severity: Insights from a Sequential Analysis in NHPI Populations in Hawaii. Accepted for poster presentation at SLEEP 2025, the 39th Annual Meeting of the Associated Professional Sleep Societies, Seattle, Washington on June 8-11, 2025

Nicholas Anderson, MD, Tamlyn Sasaki, BS, Cierra Nakamura, BS, Meliza Roman, MS, Hyeong Jun Ahn, PhD, Enrique Carrazana, MD, Kore K. Liow, MD. (2025 June 09). Differences in Clinical Presentation of Obstructive Sleep Apnea in Native Hawaiian and Pacific Islander Patients [Poster presentation]. SLEEP 2025, Seattle, WA.

 

A Retrospective Analysis of Multiple Sclerosis Patients in Hawaii: How Do Caucasians Compare with Other Ethnocultural Groups? . .Bellatti S, Romero J, Muniz S, Chang E, Hong B, Nakamura R, Cheung AJ, Wright DD, Ishikawa K, Carrazana E, Liow K. Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Forum 2025. Poster 168. West Palm Beach,  FL. February 27, 2025

 

Native Hawaiian and Pacific Islander Participation In Alzheimer’s Disease Clinical Trials: Exploration Of Zip Code Based Heat Map Patterns. Nina Krupa, Kylie Herndon, Kaelyn Pacpaco, D-Dré D. Wright, Ryan Nakamura, Anita J. Cheung, Mph, Anson Y. Lee, Julia R. Jahansooz, Masako Matsunaga, Phd, Samuel T. Kim, Enrique Carrazana,, Kore Liow. AD/PD April 2025. Vienna AUSTRIA

 

A Real-World Point of Care EEG/ERP Biomarker Platform for Assessment of The Neurophysiological Deficits in Individuals with Mild Cognitive Impairment.  Liow K, Nakahira S, Borrello K, Bow-Keola J, Yamauchi K, Read M, Hogue S, Carrazana E, Abramowitz J, Kim S, Zhi Q, Foster G, Ma C, Kovacevic N, Meghdadi A, Berka C. Alzheimer’s Association International Conference (AAIC)- Advancements: Modernizing Diagnosis, Modernizing Diagnosis using Real World Applications Case Studies, September 18th, 2024, Tokyo, JAPAN

 

The Safety and Effectiveness of Dual Calcitonin Gene-Related Peptide (CGRP) Therapies for Migraine Treatment: A Focus on Small Molecule Antagonist and Ligand Monoclonal Combinations. Ho Hyun Lee, Anita J Cheung,, Julia R Jahansooz, Edward J Weldon, Anson Y Lee, Kyle M Ishikawa, Nicole Little, Enrique Carrazana, , Kore K Liow. Migraine Trust International Symposium September, 2024. London, ENGLAND.

 

Pharmacokinetics and tolerability of single-dose Staccato® alprazolam in adolescents with epilepsy and population PK analysis to support dose selection in adolescents Klein, Pave; Aungaroon, Gewalin; Biton, Victor; Liow, Kore Kai; Phillips, Steven; Wychowski, Thomas6; Sadek, Ahmed; Elshoff, Jan-Peer; Roebling, Robert; King, Aliceson; Ford, Andrea10; Rospo, Chiara C; Schoemaker, Rik; Chanteux, Hugues. 15th European Epilepsy Congress (EEC), Rome, Italy. September, 2024

 

A Real-World Point of Care EEG/ERP Biomarker Platform for Assessment of The Neurophysiological Deficits in Individuals with Mild Cognitive Impairment.  Liow K, Nakahira S, Borrello K, Bow-Keola J, Yamauchi K, Read M, Hogue S, Carrazana E, Abramowitz J, Kim S, Zhi Q, Foster G, Ma C, Kovacevic N, Meghdadi A, Berka C.. Poster presentation at Alzheimer’s Association International Conference, Philadelphia, PA. July 2024.2024

 

Cheung AJ, Nishimura  MK, Miyaki KJ, Stephens TA, Weldon EJ, Jahansooz JR, Lee AY, Matsunaga M, Chang JC, Carrazana E, Viereck V, Liow KK. Exploring Radiculopathy in Underserved Communities: A Focus on AANHPI Populations and Risk Factors. Neurology 102 (17_supplement_1), 5405 American Academy of Neurology 2024 Annual Meeting, April 15, 2024 Denver, CO

 

The Safety and Efficacy of Dual Calcitonin Gene-Related Peptide Therapies for Migraine Treatment. Ho Hyun Lee, Reyn Yoshioka, Man Ian Woo, Lana Liquard, Julia Jahansooz, Edward Weldon, Anson Lee, Kyle Ishikawa, Nicole Little, Enrique Carrazana, Jason Viereck, Kore Liow. Neurology 102 (17_supplement_1), 3820 American Academy Neurology Meeting, 2024 April.

 

Pharmacokinetics and Tolerability of Single-dose Staccato® Alprazolam in Adolescents with Epilepsy and Population PK Analysis to Support Dose Selection in Adolescents. American Academy Neurology Meeting, 2024 April.

 

Tobacco, Marijuana, and Antidepressant Use Prior to Concussion Are Associated with Increased Depression Risk in Post-concussive Syndrome Patients. Eli Snyder, Ryan Nakamura, Miriya Ogawa, Kaylin Bersamin, Edward Weldon, Julia Jahansooz, Anson Lee, Kyle Ishikawa, Janette Abramowitz, Enrique Carrazana, Jason Viereck, Kore Liow. Neurology 102 (17_supplement_1), 3832. American Academy of Neurology 2024 Annual Meeting; April 14, 2024; Denver, CO.

 

VNS in Lennox-Gastaut Syndrome: Real-world Experience from CORE-VNS (P3-1.014) Paul Lyons, James Wheless, Ryan Verner, Jose Ferreira, Kore Liow, James Valeriano, Gholam K. Motamedi, Neurology 102 (17_supplement_1), 6902. American Academy Neurology Meeting, 2024 April.

 

Factors Associated with Depression Risk in Post-Concussive Syndrome Patients in Hawaii. 2024.  Eli Snyder, Ryan Nakamura, Miriya Ogawa, Kaylin Bersamin, Edward Weldon, Julia Jahansooz, Anson Lee, Kyle Ishikawa, Janette Abramowitz, Enrique Carrazana, Jason Viereck,, Kore Liow. American Neuropsychiatric Association 34th Annual Meeting; March 8, 2024; Houston, TX

Progression of Parkinson’s Disease in Asian and Native Hawaiian and Pacific Islander Populations. Borrello K, Nakahira S, Fontana P, Giuttu D, Hunter C, Jahansooz JR, Weldon EJ, Lee AY, Roman M, Ahn HJ, Viereck J, Carrazana E, Liow K. Poster presentation at International Conference on Alzheimer’s and Parkinson’s Diseases and related neurological disorders (ADPD), Lisbon, Portugal. March 2024.

 

EEG slowing and CSF amyloid status: Implications for Alzheimer’s disease detection and progression. Kim, Nathan K, Nakahira S, Lee A, Carrazana E, Viereck J, Liow K Journal of the Neurological Sciences, 2023 Dec Volume 455, 121409

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